Computational Lithography empowering Microchip Advancements: Revolutionizing Chip Design

Semiconductor industry is soaked with one of the most ever-advancing technologies. The demand for smaller, faster, and more efficient microchips keeps the world of semiconductors on its toes. Computational lithography has totally revolutionized the field by meeting the desired level of precision and complexity in chip design.

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Chip-scale Optical Quantum Simulation System: Quantum Computing Milestone

A team of researchers have successfully simulated complex natural phenomena at the quantum level. Scientists at the University of Rochester’s Hajim School of Engineering & Applied Sciences have developed a chip-scale optical quantum simulation system. Conventionally, photonics-based computing involves controlling the paths of photons. This time, the team led by Qiang Lin has taken a different approach. According to which, they have simulated the phenomena in a synthetic space. And they have manipulated the frequency, or color, of quantum entangled photons as time progresses.

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RNA-Guided Endonucleases in Eukaryotes: Genetic Tools found in Nature

An international team of researchers has identified a programmable RNA-guided system in eukaryotes. Eukaryotes encompass plants, animals, fungi, and protists. The newly discovered system is based on a protein called Fanzor. It uses RNA as a guide to precisely target DNA. The researchers demonstrated that Fanzor proteins can be reprogrammed to edit the genome of human cells. Compared to CRISPR/Cas systems, the Fanzor system is more compact and has the potential to be delivered more easily to cells and tissues as therapeutics.

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Biodegradable Gel shows promise for Cartilage Regeneration: Biomaterial Engineering

One of the biggest challenges that still haunts tissue engineering and regenerative medicine is, how to mimic the properties of articular cartilage in synthetic materials. Articular cartilage possesses a unique combination of stiffness and toughness. These features allow the connective tissues to withstand the mechanical stresses and strains experienced during joint movement.

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ILT and SMO continue to push the Boundaries of Resolution: Semiconductor Manufacturing

Semiconductor manufacturing is experiencing rapid and dynamic growth. The exponential evolution is making it one of the most swiftly evolving industries globally. As technology is advancing, the electronic devices are progressively shrinking in size. Behind this constant innovation lies the incredible field of “computational lithography”. It is the heart of semiconductor industry. After all, it blends the power of computers, mathematics, and precision engineering. Only to create intricate microscale structures on silicon wafers.

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DNA Damage Repaired through Antioxidant Enzymes: Genetic Restoration

At the fundamental level, function of human cell is to convert nutrients into energy and useful products that sustain life. In the process, these cells give out certain waste products that otherwise cause harm to the inner environment. For instance, reactive oxygen species (ROS) molecule is one of the natural byproducts of cellular metabolism. ROS are highly reactive molecules that contain oxygen atoms with unpaired electrons.

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Interview: Dr. Kai Wang Materials Scientist at The Penn State

Dr. Kai Wang is PhD, Principal Investigator, and Assistant Research Professor at the Department of Materials Science and Engineering, Penn State. His recent work on intelligent and efficient panchromatic imaging for artificial retina biotechnology, caught our attention and so we tried to touch base with him for an interview. We got lucky, as he agreed to spend some time with us. Dr. Wang, here, talks about his quest to understand the mechanisms of cognition within the neural topological structures of the brain. And how these natural intelligences can be influenced…

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Protein-based Nano Device to Influence Cell Behaviour: Synthetic Biology

Conventional methods in synthetic biology for cell-based therapies focus on using specific proteins to achieve a desired effect in cells. For instance, cancer treatment involves certain proteins to kill cancer cells. while, some proteins are used to help tissues regenerate after an injury. This process, however, is lengthy as it takes time for the proteins to be produced and break down. Additionally, it requires a lot of energy from the cells.

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An Organic Electrochemical Transistor: AI Hardware

Lately, there has been growing interest in creating brain-inspired hardware for enhancing efficiency of AI models.  Conventional hardware architectures are specialized in three specific tasks, which are: Researches across the globe, however, are exploring the possibility of combining these functionalities into a single device. They aim to mimic the parallel and distributed nature of the human brain.

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Biomolecular Condensates possesses an Electric Potential: Biological Chemistry

Electrical charges have a vital role in majority of biological processes in the human body. In fact, the human body is an incredibly complex electrical system that relies on the flow of electrical charges to carry out its functions. Electrical signals, for instance, are not only used by the brain and nerves to communicate with each other. But the same signals also allow us to move our muscles, feel sensations, and think. At the cellular level, ions such as sodium, potassium, and calcium work in tandem to regulate various processes…

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Piezoelectric Effect observed in Ionic Liquids: Pressure Electricity

Certain materials like crystals, ceramics, and at times even biological matter (bone, DNA, and proteins), can generate an electrical charge. The effect is seen when the material is put under the influence of some mechanical stress – such as pressure or vibration – this phenomenon is termed as piezoelectricity. The charge is accumulated on the surface of the material. From there, it can be used for various applications.

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Gas Entrapping Materials to Mitigate Tumor Hypoxia: GeM Technology

Cancer treatments such as radiotherapy and chemotherapy have been shown to be less effective when exposed to a hypoxic environment. In fact, low oxygen levels in tumors can also escalate disease progression. Hyperbaric oxygen therapy and microbubble infusion are the two techniques through which oxygen levels in tumors can be increased to improve treatment outcomes.

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