Distinct Activation Patterns of Projection Neurons: Cortical Dynamics

Cerebral cortex is the outer layer of cerebrum, that is the largest part of the brain. All kinds of higher-level processes such as language, memory, and decision-making are performed in this region. The complex, densely packed structure is saturated with various types of neurons. It is extremely difficult to image its neuronal dynamics with the necessary spatial and temporal resolution. So far, fMRI (functional magnetic resonance imaging) technique is widely used for studying brain activity. However, when it comes down to examine neural circuitry at the point of a single…

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Book Review: The Immortal Life of Henrietta Lacks by Rebecca Skloot

The Immortal Life of Henrietta Lacks is a beautiful book written by Rebecca Skloot in 2010. It is about a poor African American woman who came down with a rare cervical cancer in 1950s. After giving birth to her fourth child, Henrietta grew suspicious of a lump in her cervix. To clarify things, she went straight to Johns Hopkins Hospital. The doctor took a biopsy by extracting sample cells for examination. Although she couldn’t survive, after a few sessions of x-ray therapy and radium treatment. She died at the age…

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Neuro-Stack to records Single Neuron Activity: Brain Mechanisms of Movement

New technologies have revolutionized many fields, including medicine and neuroscience. Advances in engineering, materials science, and computer technology have enabled the development of increasingly sophisticated devices for recording and analysing biological signals, such as brain activity, with unprecedented precision and accuracy. For instance, electroencephalography (EEG) is a non-invasive technique that measures electrical activity in the brain using electrodes placed on the scalp. With the advancement in electronics and computing the EEG signals can now be recorded with greater precision and resolution.

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Hydrogels Promote Neuronal Tissue Growth: Brain Healing

Degeneration of brain cells could be a natural aging process. However, destruction or deterioration of brain cells could occur due to a wide range of internal as well as external factors. In general, brain damage refers to significant, undiscriminating trauma-induced damage. Science has tremendously advanced when it comes to health care and disease control. There are new and radical developments in the field of neurology alone. One such progress is brain tissue reconstruction.

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Exon Junction Complex controls mRNA: RNA Methylation

Our gene expression is regulated by RNA methylation. Same process also affects various cellular processes like differentiation and development. Lately, University of Chicago researchers, led by Chuan He, have uncovered new insights into how genes work by solving a long-standing mystery related to RNA methylation. Researchers in Chuan He’s lab have been studying RNA methylation and its potential impact on human health for over a decade.

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Gas Entrapping Materials to Mitigate Tumor Hypoxia: GeM Technology

Cancer treatments such as radiotherapy and chemotherapy have been shown to be less effective when exposed to a hypoxic environment. In fact, low oxygen levels in tumors can also escalate disease progression. Hyperbaric oxygen therapy and microbubble infusion are the two techniques through which oxygen levels in tumors can be increased to improve treatment outcomes.

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Compact Cas7-11 Enzyme for RNA Editing: CRISPR-Cas System

The CRISPR CAS9 system famously known as genetic scissors was discovered by Emmanuelle Charpentier and Jennifer Doudna in 2012. And since then, the new tool has been studied extensively across global academia. Initial studies of the genome editing tool altered only the DNA. However, lately the CAS system is also studied for editing RNA. What is CRISPR-CAS system? CRISPR-CAS system is an adaptive immune system of bacteria, which protects it from invaders. Also, it defends the bacterial host from renewed infection as it memorizes previous infections. DNA has the fingerprint.…

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Multiple Modes of Dendritic Integration in Single Neurons: Brain Computation

Dendrites, branch like extensions protruding from a single neuron, participate in computations and permutations to give a synchronized output to the neuron. Researchers at MIT have now demonstrated that not only different types of dendrites (of a single neuron) collect input from various regions of the brain, they also process that information in different customized ways.

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Metal Eating Bacteria to Clean Up Metallic Waste: Green Mining

A starving being can eat everything and anything and within minutes. While in the character of 19th-century trapper, Leonardo DiCaprio, a starving man in The Revenant eats raw bison liver. Survival instinct is what keeps the living beings away from extinction coz of hunger and this can be seen in microorganisms as well.

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One Epidermal Patch to track Cardiovascular and Multiple Biomarkers: Wearable Microelectronics

Monitoring cardiovascular signals and multiple biochemical levels together on one tiny wearable patch has always been a far-fetched dream in the nanotech world. Scientists across the globe are still trying to figure it out however, researchers at the University of California San Diego have done something extraordinary in soft, stretchy skin patch.

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