A Scientific Research Vault
Recent research conducted by Maxwell Miner from the University of Turku in Finland, working at the Turku PET Centre, sheds light on the potential of folate receptors as a valuable tool in the field of brain tumor imaging and treatment. Folate-based radiopharmaceuticals are a type of medical imaging agent that combines folate – a form of vitamin B9 – with a radioactive substance.
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The University of Pennsylvania in Philadelphia conducted a study utilizing siRNA technology to suppress the cyclophilin A (CyPA) protein. Surprisingly, this approach not only led to a reduction in tumor size. But it also enhanced survival rates among patients diagnosed with multiple myeloma.
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At the fundamental level, function of human cell is to convert nutrients into energy and useful products that sustain life. In the process, these cells give out certain waste products that otherwise cause harm to the inner environment. For instance, reactive oxygen species (ROS) molecule is one of the natural byproducts of cellular metabolism. ROS are highly reactive molecules that contain oxygen atoms with unpaired electrons.
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Cerebral cortex is the outer layer of cerebrum, that is the largest part of the brain. All kinds of higher-level processes such as language, memory, and decision-making are performed in this region. The complex, densely packed structure is saturated with various types of neurons. It is extremely difficult to image its neuronal dynamics with the necessary spatial and temporal resolution. So far, fMRI (functional magnetic resonance imaging) technique is widely used for studying brain activity. However, when it comes down to examine neural circuitry at the point of a single…
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Parkinson’s disease (PD) is the most common neurodegenerative disease. The characteristic motor impairments are due to two main reasons:
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The Immortal Life of Henrietta Lacks is a beautiful book written by Rebecca Skloot in 2010. It is about a poor African American woman who came down with a rare cervical cancer in 1950s. After giving birth to her fourth child, Henrietta grew suspicious of a lump in her cervix. To clarify things, she went straight to Johns Hopkins Hospital. The doctor took a biopsy by extracting sample cells for examination. Although she couldn’t survive, after a few sessions of x-ray therapy and radium treatment. She died at the age…
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New technologies have revolutionized many fields, including medicine and neuroscience. Advances in engineering, materials science, and computer technology have enabled the development of increasingly sophisticated devices for recording and analysing biological signals, such as brain activity, with unprecedented precision and accuracy. For instance, electroencephalography (EEG) is a non-invasive technique that measures electrical activity in the brain using electrodes placed on the scalp. With the advancement in electronics and computing the EEG signals can now be recorded with greater precision and resolution.
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Degeneration of brain cells could be a natural aging process. However, destruction or deterioration of brain cells could occur due to a wide range of internal as well as external factors. In general, brain damage refers to significant, undiscriminating trauma-induced damage. Science has tremendously advanced when it comes to health care and disease control. There are new and radical developments in the field of neurology alone. One such progress is brain tissue reconstruction.
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Our gene expression is regulated by RNA methylation. Same process also affects various cellular processes like differentiation and development. Lately, University of Chicago researchers, led by Chuan He, have uncovered new insights into how genes work by solving a long-standing mystery related to RNA methylation. Researchers in Chuan He’s lab have been studying RNA methylation and its potential impact on human health for over a decade.
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Cancer treatments such as radiotherapy and chemotherapy have been shown to be less effective when exposed to a hypoxic environment. In fact, low oxygen levels in tumors can also escalate disease progression. Hyperbaric oxygen therapy and microbubble infusion are the two techniques through which oxygen levels in tumors can be increased to improve treatment outcomes.
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The CRISPR CAS9 system famously known as genetic scissors was discovered by Emmanuelle Charpentier and Jennifer Doudna in 2012. And since then, the new tool has been studied extensively across global academia. Initial studies of the genome editing tool altered only the DNA. However, lately the CAS system is also studied for editing RNA. What is CRISPR-CAS system? CRISPR-CAS system is an adaptive immune system of bacteria, which protects it from invaders. Also, it defends the bacterial host from renewed infection as it memorizes previous infections. DNA has the fingerprint.…
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Dendrites, branch like extensions protruding from a single neuron, participate in computations and permutations to give a synchronized output to the neuron. Researchers at MIT have now demonstrated that not only different types of dendrites (of a single neuron) collect input from various regions of the brain, they also process that information in different customized ways.
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Researchers at University College London have discovered a new form of non-invasive therapy for neurological disorders. The technique called “magnetomechanical stimulation” (MMS) involves microscopic magnetic particles for remotely stimulating brain cells.
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Structural organisation has always been the hallmark of complex organisms, this however is not the case anymore. Researchers at University of California, San Diego have discovered that bacterial biofilms are not at all simple but is a complex community, which has a direct relationship with its external settings.
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Dr Nadac Reales is Deputy Director of Innovator Services at University of Antofagasta, Chile. Additionally, she is running her own firm, the Rudanac Biotec Lab. Aim of her lab is to provide biotechnological solutions to real world problems.
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