DNA Damage Repaired through Antioxidant Enzymes: Genetic Restoration

At the fundamental level, function of human cell is to convert nutrients into energy and useful products that sustain life. In the process, these cells give out certain waste products that otherwise cause harm to the inner environment. For instance, reactive oxygen species (ROS) molecule is one of the natural byproducts of cellular metabolism. ROS are highly reactive molecules that contain oxygen atoms with unpaired electrons.

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Interview: Dr. Kai Wang Materials Scientist at The Penn State

Dr. Kai Wang is PhD, Principal Investigator, and Assistant Research Professor at the Department of Materials Science and Engineering, Penn State. His recent work on intelligent and efficient panchromatic imaging for artificial retina biotechnology, caught our attention and so we tried to touch base with him for an interview. We got lucky, as he agreed to spend some time with us. Dr. Wang, here, talks about his quest to understand the mechanisms of cognition within the neural topological structures of the brain. And how these natural intelligences can be influenced…

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Protein-based Nano Device to Influence Cell Behaviour: Synthetic Biology

Conventional methods in synthetic biology for cell-based therapies focus on using specific proteins to achieve a desired effect in cells. For instance, cancer treatment involves certain proteins to kill cancer cells. while, some proteins are used to help tissues regenerate after an injury. This process, however, is lengthy as it takes time for the proteins to be produced and break down. Additionally, it requires a lot of energy from the cells.

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An Organic Electrochemical Transistor: AI Hardware

Lately, there has been growing interest in creating brain-inspired hardware for enhancing efficiency of AI models.  Conventional hardware architectures are specialized in three specific tasks, which are: Researches across the globe, however, are exploring the possibility of combining these functionalities into a single device. They aim to mimic the parallel and distributed nature of the human brain.

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Biomolecular Condensates possesses an Electric Potential: Biological Chemistry

Electrical charges have a vital role in majority of biological processes in the human body. In fact, the human body is an incredibly complex electrical system that relies on the flow of electrical charges to carry out its functions. Electrical signals, for instance, are not only used by the brain and nerves to communicate with each other. But the same signals also allow us to move our muscles, feel sensations, and think. At the cellular level, ions such as sodium, potassium, and calcium work in tandem to regulate various processes…

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Piezoelectric Effect observed in Ionic Liquids: Pressure Electricity

Certain materials like crystals, ceramics, and at times even biological matter (bone, DNA, and proteins), can generate an electrical charge. The effect is seen when the material is put under the influence of some mechanical stress – such as pressure or vibration – this phenomenon is termed as piezoelectricity. The charge is accumulated on the surface of the material. From there, it can be used for various applications.

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Gas Entrapping Materials to Mitigate Tumor Hypoxia: GeM Technology

Cancer treatments such as radiotherapy and chemotherapy have been shown to be less effective when exposed to a hypoxic environment. In fact, low oxygen levels in tumors can also escalate disease progression. Hyperbaric oxygen therapy and microbubble infusion are the two techniques through which oxygen levels in tumors can be increased to improve treatment outcomes.

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Wearable Electrotactile Feedback System: Skin VR

Haptic systems are mainly designed to control virtual objects. Their efficacy is good, but when it comes to controllers, joysticks, and steering wheels, things look slightly bulky. And tangled wires is another task to deal with. Researchers at City University of Hong Kong have come up with a portable solution to enhance the tactile VR experience.

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Butterfly Robots with Bistable Wings: Biomimicry

In an effort to create faster and more energy-efficient soft robots, researchers at North Carolina State University have created a prototype of swimming soft robots based on manta rays. The team got inspired from the biomechanics of the marine animal. Rate of swimming for most of the (swimming) soft robot is one body length per second, manta rays, however, glide at much faster rate. Their swimming efficiency triggered the scientists to look into the potentiality of creating a similar robot, biomechanically.

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Interview: Dr Philipp Simons, Materials Scientist at Massachusetts Institute of Technology

Dr. Philipp Simons recently hit headlines with his new paper on miniature glucose fuel cells for implantable devices. According to him, human body is saturated with glucose hence, harvesting this energy to power implantable devices is an achievable feat. Dr. Jennifer L.M. Rupp from Technical University Munich in Germany, also Dr. Simons’ thesis supervisor, postulated that battery takes up 90% of an implant’s volume. Interestingly, the new fuel cell will mask the implant and power it with no volumetric footprint. Their innovative approach to solve medical problem gave me an…

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Shapeshifting Nanobots to Brush and Floss Teeth: Toothbrushing Microbots

Toothbrush, or the heads per say, have not much evolved since ages, from rectangular they have only graduated to diamond shaped geometry. I really doubt how far does the new shape has been able to reach the teeth in the back. In the dental hygiene sequence floss, brush and rinse go hand in hand. And each step is an important and at times, cumbersome task especially for people with disabilities. Researchers at the University of Pennsylvania have put in an effort to combine these three steps in one with the…

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The Ear-EEG Measure How Astronauts Sleep: Sleep in Orbit

Sleep is the most vital process for overall mental development. Irrespective of age, sleep deprivation leads not only to mood fluctuations the next day but it also affects the overall productivity including decision-making skills, creativity and judgment.  Astronauts who spend quite some time in zero gravity face issues while maintaining normal sleep patterns. Even an artificial day-night cycle does not help them in keeping up with a natural circadian rhythm.  Therefore, to get more understanding in the brain’s electrical activity and map sleep patterns, researchers at Aarhus University have developed…

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Compact Cas7-11 Enzyme for RNA Editing: CRISPR-Cas System

The CRISPR CAS9 system famously known as genetic scissors was discovered by Emmanuelle Charpentier and Jennifer Doudna in 2012. And since then, the new tool has been studied extensively across global academia. Initial studies of the genome editing tool altered only the DNA. However, lately the CAS system is also studied for editing RNA. What is CRISPR-CAS system? CRISPR-CAS system is an adaptive immune system of bacteria, which protects it from invaders. Also, it defends the bacterial host from renewed infection as it memorizes previous infections. DNA has the fingerprint.…

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